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μ-conotoxin-PIIIA Blocker of Nav1.4 channels

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  • 产品名称:μ-conotoxin-PIIIA Blocker of Nav1.4 channels
  • 产品型号:08CON006-00100
  • 产品展商:其他品牌
  • 产品文档:无相关文档
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产品描述
μ-conotoxin-PIIIA Blocker of Nav1.4 channels μ-Conotoxin PIIIA (mu-conotoxin PIIIA) is a conotoxin that has been isolated from the venom of the cone Conus purpurascens. μ-conotoxin PIIIA demonstrates a higher affinity for the mammalian muscle sodium channel Nav1.4 (IC50 ~ 44 nM) than for the CNS Nav1.2 subtype (IC50 ~ 640 nm). μ-Conotoxin PIIIA blocks more irreversibly amphibian muscle sodium channels than mammalian ones.
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