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Cy5-ProTx-II Fluorescent Nav1.7 blocker

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  • 产品名称:Cy5-ProTx-II Fluorescent Nav1.7 blocker
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Cy5-ProTx-II Fluorescent Nav1.7 blocker Cy5-ProTx-II is a fluorescently labeled ProTx-II, a famous Nav1.7 blocker. The wild type ProTx-II blocks Nav1.7 with an IC50 value of around 300 pM, Nav1.2, Nav1.5 and Nav1.6 with IC50 values of 41 nM, 79 nM and 26 nM respectively. The Cy5-ProTx-II version developed by Smartox has potent Nav1.7 blocking activity. It was shown to fully block Nav1.7 at 100 nM concentration.
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