Smartox Biotechnology 主营:Smartox Biotechnology授权代理商
服务电话: 021-52271579
联系我们
产品中心
所在位置:

OD1 OD1, a potent Nav1.7 channel activator

  • 如果您对该产品感兴趣的话,可以
  • 产品名称:OD1 OD1, a potent Nav1.7 channel activator
  • 产品型号:
  • 产品展商:其他品牌
  • 产品文档:无相关文档
简单介绍

产品描述
OD1 OD1, a potent Nav1.7 channel activator OD1 is a scorpion peptide that has been isolated initially from the venom of the scorpion Odonthobuthus doriae. OD1 potently inhibits fast inactivation of mammalian channels Nav1.7 (EC50 4.5 nM), Nav1.4 (EC50 10 ± 2 nM) and Nav1.6 (EC50 47 ± 10 nM). OD1 also blocks fast inactivation of the para/tipE insect channel (EC50 80 nM). OD1 weakly affects mammalian Nav1.3 and Nav1.5 (EC50 > 1 μM) and does not affect Nav1.2 and Nav1.8. OD1 induces spontaneous pain when injected in animal in association with our without Veratridine and can be used to test the analgesic effects of Nav1.7 blockers in-vivo.
产品留言
标题
联系人
联系电话
内容
验证码
点击换一张
注:1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!