Smartox Biotechnology 主营:Smartox Biotechnology授权代理商
服务电话: 021-52271579
联系我们
产品中心
所在位置:

Apamin Apamin is a SK channel blocker

  • 如果您对该产品感兴趣的话,可以
  • 产品名称:Apamin Apamin is a SK channel blocker
  • 产品型号:08APA001-00500
  • 产品展商:其他品牌
  • 产品文档:无相关文档
简单介绍

产品描述
Apamin Apamin is a SK channel blocker Apamin is a neurotoxin that was originally isolated from Apis mellifera. Apamin binds to and inhibits the SK channels (small conductance Ca2+-activated K+ channels) in the brain and spinal cord. Apamin inhibits three subtypes of SK channels (KCa2.1, KCa2.2, and KCa2.3) with different affinity. Apamin does not affect KCa3.1 channel activity. Apamin most likely acts as a pore blocker such as Scyllatoxin or Tamapin, although residues both inside and outside of the pore region of the SK channels participate in apamin binding. The SK channels are present in a wide range of excitable and non-excitable cells, including cells in the central nervous system, intestinal myocytes, endothelial cells, and hepatocytes.
产品留言
标题
联系人
联系电话
内容
验证码
点击换一张
注:1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!