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Leiurotoxin-1 Dab7 SK2 channel blocker

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  • 产品名称:Leiurotoxin-1 Dab7 SK2 channel blocker
  • 产品型号:LED01-00100
  • 产品展商:其他品牌
  • 产品文档:无相关文档
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Leiurotoxin-1 Dab7 SK2 channel blocker Leiuorotoxin-Dab7 (Lei-Dab7) is a mutated version of Leiurotoxin, a peptide identified from the venom of the scorpion Leiurus quinquestriatus hebraeus. The Dab amino acid in position 7 confers to this compound a high selectivity for SK2 channels among other channels. Lei-Dab7 exhibits > 200 fold selectivity for SK2 over SK1, SK3, IK, Kv and Kir channels. The IC50 for SK2 is about 3 nM.
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