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产品详情
  • 产品名称:ω-Conotoxin-MVIIC Blocker of P/Q and N-type Ca2+ channels

  • 产品型号:08CON002-00100
  • 产品厂商:
  • 产品价格:0
  • 折扣价格:0
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详情介绍:
ω-Conotoxin-MVIIC Blocker of P/Q and N-type Ca2+ channels ω-conotoxin MVIIC (omega conotoxin MVIIC) is a conotoxin that has been isolated from the venom of the cone Conus magus. ω-conotoxin MVIIC is a blocker of P/Q (IC50=35 nM) and N-type calcium channels. It inhibits presynaptic Ca2+ channels, including the Ca2+ channels responsible for Ca2+ uptake by rat brain synaptosomes, the P-type Ca2+ channels in cerebellar Purkinje cells, and a significant fraction of ω-conotoxin GVIA-resistant currents in hippocampal CA1 neurons. ω-conotoxin MVIIC also presents an inhibition of ω-conotoxin GVIA-resistant depolarization-induced neurotransmitter release in cerebellar neurons of rats.
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