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Waglerin-1-FAM Waglerin-1 blocks muscle nAChRs

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  • 产品名称:Waglerin-1-FAM Waglerin-1 blocks muscle nAChRs
  • 产品型号:WAG002-01000
  • 产品展商:其他品牌
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Waglerin-1-FAM Waglerin-1 blocks muscle nAChRs Waglerin-1 (Wtx-1) is a peptide originally isolated from the venom of the Wagler’s pit viper (Trimeresurus wagleri). This 22 amino-acid peptide is a competitive antagonist of ***** muscle nicotinic acetylcholine receptors. Waglerin-1 binds selectively to epsilon subunit of nAChR. Some studies have demonstrated that Waglerin-1 has an effect on ionotropic GABA receptors. It may potentiate or depress I(GABA) depending on the neurons. Some derivatives of Waglerin-1 are currently used in cosmetics to reduce wrinkles. The fluorescent derivative Waglerin-1-FAM can be use to explore the expression and function of the ***** nAChR subtypes.
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